Bo Jackson On Being The Greatest Athlete Of All Time + His Prostate Cancer Story | Bussin'

Bussin' With The Boys44mApril 2, 2026

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AI-Generated Summary

Bo Jackson, widely regarded as one of the greatest athletes of all time, opens up about his prostate cancer diagnosis and the decision to have his prostate removed in October—prioritizing time with his family over fear of losing his sex life. He reveals that the decision wasn't about ego or legacy, but about being present for his four-year-old and two-year-old grandsons, who he wants to watch grow up. Jackson uses his platform to break the stigma around men’s health, calling out the toxic masculinity that silences men from discussing prostate issues, colonoscopies, or even breast cancer. He shares a harrowing personal story from age 20 when he discovered blood in his stool—leading to a colonoscopy that found a benign polyp, which ultimately saved his life. Now 63, he’s had over 15 colonoscopies and insists men should get screened earlier, especially if there’s a family history. He also recounts his legendary 4.13-second 40-yard dash at Auburn, a moment he downplays but which remains one of the most debated in NFL history. Beyond sports, Jackson emphasizes that his greatest legacy isn’t fame, but the quiet, private acts of kindness he’s done for others—living a life of service, not spotlight.

Key Takeaways
1

Bo Jackson had his prostate removed in October, choosing to prioritize family over fear of losing his sex life.

2

Men should get prostate screenings starting at age 40, or earlier if there’s a family history of cancer.

3

Blood in the stool at age 20 led to a colonoscopy that found a polyp—saving Jackson’s life decades later.

4

Jackson ran a 4.13-second 40-yard dash at Auburn, a time never officially verified but widely believed.

5

He refuses to claim he’s the greatest athlete of all time, instead honoring Deion Sanders and focusing on legacy through service.

…and 3 more takeaways available in PodZeus

Chapters
0:00
5 min

Intro & Sponsor Teases

The episode opens with a series of ad reads for unrelated podcasts including Hey Jonas, Humor Me, and Soccer Moms, followed by a brief intro to Bussin' with the Boys and its sponsors.

4:50
5 min

Bo Jackson’s Health Mission

I had my prostate taken out in October. This past October, I had my prostate taken up. I never for once sat up and said, oh, no, I don't want to do it because it's going to ruin my sex life.

Highlight
10:00
10 min

The Stigma of Men’s Health

We don't talk about that because it's taboo. I want to use my platform to peel the layers off of that onion so we can talk about it.

Highlight
20:00
10 min

Personal Health Journey

If I had ignored like we all do as young guys who think that we are invincible, we know everything. If I just said, oh, that's probably nothing, so I'm not going to bother. I wouldn't be here right now.

Highlight
30:00
10 min

Legacy Beyond Sports

I love being private. I don't have to be out there, look at me, hey, this is me. I hate that.

Highlight
High-Impact Quotes
I would give my life if I could hug and kiss my mom again. Period. Period.
Bo Jackson45:54
Viral: 90.0
prostate taken out in October. This past October? This past October, I had my prostate taken up. I never for once sat up and said, oh, no, I don't want to do it because it's going to ruin my sex life.
Bo Jackson12:32
Viral: 88.0
We don't talk about that because it's taboo. I want to use my platform to peel the layers off of that onion so we can talk about it.
Bo Jackson10:32
Viral: 85.0
Speakers

Host

Jonas Brothers

Guest

Bo Jackson
Topics Discussed
men's health95%prostate cancer90%colon cancer85%dual sport athlete80%40-yard dash75%sports legacy70%toxic masculinity65%health screening60%
People & Brands

Bo Jackson

person

12xPositive

Auburn University

organization

4xNeutral

University of Alabama

organization

3xNeutral

Deion Sanders

person

3xPositive

Bud Light

brand

3xNeutral

Raiders

organization

2xNeutral

Terry Robisky

person

2xPositive

Seattle Seahawks

organization

2xNeutral

Brian Bosworth

person

2xNeutral

FanDuel Sportsbook

brand

2xNeutral

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