Can You Have Your Cake and Drink Wine, Too?

Chasing Life14mJune 16, 2026
AI-Generated Summary

The episode tackles two viral health myths head-on: whether a glass of red wine is worse for you than eating sugar, and if heating honey in hot water makes it toxic. Contrary to popular belief, the sugar in a standard glass of dry red wine—just one gram—is minimal compared to a soda’s 37 grams or a banana’s 15 grams. But the real issue isn’t the sugar—it’s how alcohol hijacks the liver, slowing fat and carbohydrate metabolism and potentially leading to weight gain. Meanwhile, the claim that heating honey creates toxic levels of HMF (hydroxymethylfurfural) is debunked: while HMF does form when honey is heated or stored long-term, the levels in tea are negligible and far below what you get from coffee, bread, or cereal. The real risks with honey are infant botulism and calorie content—21 calories per teaspoon. The episode concludes with a powerful personal story from Amanda Peet about grief, loss, and resilience, underscoring the emotional weight behind health decisions.

Key Takeaways
1

A glass of dry red wine contains only 1 gram of sugar—less than a quarter teaspoon—making it far lower in sugar than soda, banana, or cheesecake.

2

Alcohol slows down your liver’s metabolism, causing fat and carbs to be stored as body fat, making it metabolically worse than sugar even if the sugar content is similar.

3

Honey does not become toxic when heated in tea; HMF levels are trivial compared to those in coffee, bread, and breakfast cereals.

4

Heating honey may reduce some beneficial enzymes and antioxidants, but the health impact is minimal for adults.

5

Never give honey to infants under 12 months due to the risk of infant botulism.

…and 3 more takeaways available in PodZeus

Chapters
0:03
1 min

Welcome to Paging Dr. Gupta

Introduction to the show and the first listener question about wine vs. sugar.

1:32
3 min

Is Wine Sugar Worse Than Food Sugar?

When your body is busy with breaking down alcohol, it's going to disrupt certain chemical reactions that would otherwise be breaking down fat.

Highlight
4:26
2 min

The Metabolic Cost of Alcohol

Discussion of how alcohol slows metabolism, increases appetite, and contributes to abdominal obesity.

6:23
1 min

Sponsor: CNN Weather App

Promotion of the CNN Weather app with features like real-time storm coverage and photo of the day.

7:31
1 min

Honey in Hot Water: Myth or Reality?

Honey does become toxic at certain temperatures or time over 104.

Highlight
High-Impact Quotes
The HMF exposure, this particular compound that people are worried about, that HMF exposure is trivial compared to what you're already getting from regular items, your morning toast, your baked goods, breakfast cereals, your coffee.
Dr. Kantha Schelke11:49
I was really at a remove. Like I was watching it from some kind of altitude, maybe for both things like the cancer and also felt like a weird sense of like I'm stealing bases.
Amanda Peet13:40
First off, when your body is busy with breaking down alcohol, it's going to disrupt certain chemical reactions that would otherwise be breaking down fat.
Dr. Sanjay Gupta4:26
Speakers

Host

Michael Ian Black

Guest

Amanda Peet
Topics Discussed
grief and loss95%alcohol metabolism90%honey heating myth88%wine sugar content85%health myths on social media82%HMF in food80%calorie content of honey75%infant botulism70%
People & Brands

Sanjay Gupta

person

12xNeutral

Michael Ian Black

person

8xNeutral

Dr. Kantha Schelke

person

6xNeutral

Amanda Peet

person

5xPositive

USDA

organization

4xNeutral

CNN Weather app

product

3xPositive

Anderson Cooper

person

2xNeutral

All There Is

media

2xPositive

American Heart Association

organization

2xNeutral

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