Can You Have Your Cake and Drink Wine, Too?
The episode tackles two viral health myths head-on: whether a glass of red wine is worse for you than eating sugar, and if heating honey in hot water makes it toxic. Contrary to popular belief, the sugar in a standard glass of dry red wine—just one gram—is minimal compared to a soda’s 37 grams or a banana’s 15 grams. But the real issue isn’t the sugar—it’s how alcohol hijacks the liver, slowing fat and carbohydrate metabolism and potentially leading to weight gain. Meanwhile, the claim that heating honey creates toxic levels of HMF (hydroxymethylfurfural) is debunked: while HMF does form when honey is heated or stored long-term, the levels in tea are negligible and far below what you get from coffee, bread, or cereal. The real risks with honey are infant botulism and calorie content—21 calories per teaspoon. The episode concludes with a powerful personal story from Amanda Peet about grief, loss, and resilience, underscoring the emotional weight behind health decisions.
A glass of dry red wine contains only 1 gram of sugar—less than a quarter teaspoon—making it far lower in sugar than soda, banana, or cheesecake.
Alcohol slows down your liver’s metabolism, causing fat and carbs to be stored as body fat, making it metabolically worse than sugar even if the sugar content is similar.
Honey does not become toxic when heated in tea; HMF levels are trivial compared to those in coffee, bread, and breakfast cereals.
Heating honey may reduce some beneficial enzymes and antioxidants, but the health impact is minimal for adults.
Never give honey to infants under 12 months due to the risk of infant botulism.
…and 3 more takeaways available in PodZeus
Welcome to Paging Dr. Gupta
Introduction to the show and the first listener question about wine vs. sugar.
Is Wine Sugar Worse Than Food Sugar?
“When your body is busy with breaking down alcohol, it's going to disrupt certain chemical reactions that would otherwise be breaking down fat.”
The Metabolic Cost of Alcohol
Discussion of how alcohol slows metabolism, increases appetite, and contributes to abdominal obesity.
Sponsor: CNN Weather App
Promotion of the CNN Weather app with features like real-time storm coverage and photo of the day.
Honey in Hot Water: Myth or Reality?
“Honey does become toxic at certain temperatures or time over 104.”
“The HMF exposure, this particular compound that people are worried about, that HMF exposure is trivial compared to what you're already getting from regular items, your morning toast, your baked goods, breakfast cereals, your coffee.”
“I was really at a remove. Like I was watching it from some kind of altitude, maybe for both things like the cancer and also felt like a weird sense of like I'm stealing bases.”
“First off, when your body is busy with breaking down alcohol, it's going to disrupt certain chemical reactions that would otherwise be breaking down fat.”
Host
Guest
Sanjay Gupta
person
Michael Ian Black
person
Dr. Kantha Schelke
person
Amanda Peet
person
USDA
organization
CNN Weather app
product
Anderson Cooper
person
All There Is
media
American Heart Association
organization
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