New Treatments for Recurrent Implantation Failure with guest Dr. Jenna Turocy

The Egg Whisperer Show14mJune 12, 2026
AI-Generated Summary

Recurrent implantation failure isn't a personal shortcoming—it's a medical condition, and the most promising new treatments are reshaping how we approach it. Dr. Jenna Turocy, a fertility specialist and biomedical engineer turned reproductive scientist, reveals that cutting-edge therapies like intrauterine platelet-rich plasma (PRP), peripheral blood mononuclear cell infusions, and subcutaneous granulocyte colony-stimulating factor (GCSF) are showing real promise in improving implantation rates—especially for patients with thin endometrial linings or a history of multiple failed transfers. But she also delivers a sobering warning: gene-editing tools like CRISPR, while scientifically fascinating, remain dangerously unready for clinical use, with one-third of embryos losing entire chromosomes during experimental editing. Her research underscores a critical truth: innovation must be tempered by caution. Patients, she insists, should advocate for themselves—not for experimental gene fixes, but for evidence-backed treatments like PRP and immune modulation, and to seek out specialists who stay current on the latest science. This episode is a call to action: stop blaming yourself, start demanding better care. The conversation shifts from lab bench to bedside with practical, patient-centered strategies. PRP, drawn from a patient’s own blood and injected into the uterus, acts like a regenerative 'growth cocktail' that thickens the uterine lining.

Key Takeaways
1

Recurrent implantation failure is a medical condition, not a personal failure—patients should stop blaming themselves.

2

Intrauterine platelet-rich plasma (PRP) can thicken a thin endometrial lining and improve implantation success in patients with recurrent implantation failure.

3

Subcutaneous GCSF injections show promise in improving pregnancy rates, but intrauterine GCSF does not—and may be ineffective.

4

CRISPR gene editing in embryos causes chromosomal loss in ~1/3 of cases, making it unsafe for clinical use today.

5

Patients should ask their fertility doctors about PRP, immune cell therapy, and GCSF if they’ve had multiple failed transfers.

…and 3 more takeaways available in PodZeus

Chapters
0:00
2 min

Welcome & Introduction to Dr. Jenna Turocy

Dr. Amy introduces the episode and welcomes Dr. Jenna Turocy, a fertility specialist and biomedical engineer, highlighting her groundbreaking work in genomic medicine and recurrent implantation failure.

2:10
2 min

From Biomedical Engineering to Fertility Medicine

Dr. Turocy shares her journey from biomedical engineering to fertility care, emphasizing her passion for using technology to transform lives through reproductive science.

3:50
2 min

Genomic Medicine & the Ethics of CRISPR

Approximately one third of the embryos lost an entire chromosome after being injected with CRISPR. That's not compatible with life.

Highlight
5:40
3 min

Reframing Recurrent Implantation Failure

I hate the word failure. Don't you agree? ... It's a disease and fertility is a disease.

Highlight
8:20
3 min

PRP Therapy: Regenerating the Uterine Lining

Think about like growth factors. So what the platelets are doing is they're stimulating growth factors so to help tissue grow and rejuvenate.

Highlight
High-Impact Quotes
Approximately one third of the embryos lost an entire chromosome after being injected with CRISPR. That's not compatible with life.
Dr. Jenna Turocy3:32
So I tell patients, think about like growth factors. So what the platelets are doing is they're stimulating growth factors so to help tissue grow and rejuvenate.
Dr. Jenna Turocy9:22
So these studies have actually shown that GCSF in the uterus doesn't really help.
Dr. Jenna Turocy11:51
Speakers

Host

Dr. Amy

Guest

Dr. Jenna Turocy
Topics Discussed
recurrent implantation failure95%platelet-rich plasma fertility90%thin endometrial lining88%immune therapies fertility85%fertility patient advocacy82%granulocyte colony stimulating factor80%genomic medicine fertility75%crispr fertility research70%
People & Brands

Dr. Jenna Turocy

person

12xPositive

Dr. Amy

person

10xPositive

platelet-rich plasma

other

6xPositive

granulocyte colony stimulating factor

other

5xNeutral

CRISPR

other

5xNeutral

peripheral blood mononuclear cells

other

3xPositive

Columbia University Fertility Center

organization

2xNeutral

Fertility and Sterility

other

1xNeutral

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