How to Fast for Fat Loss, Hormones, and Better Sex | Dr. Mindy Pelz

The School of Greatness1h 11mMay 15, 2026

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AI-Generated Summary

In this powerful episode of The School of Greatness, host Lewis Howes sits down with Dr. Mindy Pelz, a leading expert in fasting and hormonal health, to explore how fasting can be a transformative tool for fat loss, hormone balance, and improved sexual health—especially for women. Dr. Pelz reveals that the body operates on two energy systems: one fueled by food and another activated during fasting, which taps into fat-burning ketosis, enhances mental clarity, and slows aging. She emphasizes that fasting isn’t one-size-fits-all, particularly for women, whose hormonal cycles require a tailored approach. Drawing from her book *Fast Like a Girl*, she introduces the concept of cycling fasting in alignment with the menstrual cycle—fasting more during the first 10 days (when estrogen is high) and reducing or stopping fasting during the premenstrual phase (when progesterone is dominant). She explains how stress, poor sleep, and nighttime eating disrupt hormonal balance, while connection, oxytocin, and rest are essential for women’s well-being. Dr. Pelz shares personal and clinical stories of women regaining their cycles, fertility, and energy after adopting hormone-aligned fasting, warning that aggressive daily fasting can backfire by disrupting hormones and causing anxiety, hair loss, and cycle suppression. The episode concludes with a call to trust the body, prioritize connection, and commit to lifelong learning as pillars of true greatness.

Key Takeaways
1

Fasting is most effective when aligned with your hormonal cycle—especially for women, who should fast more during the first 10 days of their cycle and reduce or stop fasting during the premenstrual phase.

2

Nighttime eating is problematic because digestion slows during sleep, leading to poor nutrient absorption, gut imbalance, and increased fat storage—especially when melatonin is high.

3

The menstrual cycle is a natural detox process that sheds the uterine lining and helps eliminate toxins and hormones; it’s not a burden but a sign of reproductive health.

4

Women’s hormones are more complex than men’s, with estrogen, progesterone, and testosterone all pulsing in a 28-32 day rhythm—making a one-size-fits-all approach to diet and exercise ineffective.

5

Fasting can backfire for women if done too aggressively or too frequently, leading to hormonal disruption, anxiety, and loss of menstrual cycles—highlighting the need for a 'Fast Like a Girl' approach.

…and 3 more takeaways available in PodZeus

Chapters
0:00
10 min

The Two Energy Systems: Eating vs. Fasting

We have two energy systems. One where we create energy when we eat and one energy system that kicks in when we're not eating. This is where every diet has ever failed.

Highlight
10:00
10 min

Fasting Is a Training Process

Dr. Mindy emphasizes that fasting must be approached gradually, like training for a marathon. Starting with 12-hour fasts and building up allows the body to adapt, triggering hormetic stress that repairs cells and improves resilience.

20:00
10 min

Why Night Eating Is Harmful

When it's dark, the body's preparing for sleep. And so if we're eating, then two things can happen. You're more insulin resistant... and your digestive system's shutting down.

Highlight
30:00
10 min

The Female Body’s Hormonal Intelligence

Your cycle is a detox. You are shedding the inner lining of your uterus and you're getting rid of what is not serving you.

Highlight
40:00
10 min

The Fasting Cycle for Women: Fast Like a Girl

During ovulation, you get the most amount of testosterone you'll ever get. You have the most amount of estrogen you'll ever have and a little bit of progesterone.

Highlight
High-Impact Quotes
You are more powerful than you've been taught. Your body is a freaking miracle. It can heal. It can adapt. It knows what it's doing. Trust it.
Dr. Mindy Pelz68:02
Viral: 95.0
We started with when he ate, not what he ate. It's it's I didn't recognize him. It blew me away when I saw him.
Dr. Mindy Pelz63:46
Viral: 92.0
Your cycle is a detox. You are shedding the inner lining of your uterus and you're getting rid of what is not serving you.
Dr. Mindy Pelz12:17
Viral: 90.0
Speakers

Host

Lewis Howes

Guest

Dr. Mindy Pelz
Topics Discussed
Hormonal Health in Women98%Menstrual Cycle and Fasting97%Fasting for Fat Loss95%Lifestyle Alignment with Biology90%Birth Control and Hormonal Disruption88%Nighttime Eating and Digestion85%Menopause and Hormone Reset82%Oxytocin and Social Connection80%
People & Brands

Dr. Mindy Pelz

person

120xPositive

Lewis Howes

person

45xPositive

The School of Greatness

media

20xPositive

Estrogen

other

15xNeutral

Fast Like a Girl

book

15xPositive

Testosterone

other

12xNeutral

Progesterone

other

10xNeutral

YouTube

other

10xPositive

Birth Control Pill

product

8xNegative

Cortisol

other

8xNegative

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